TABLE 1.
Antibiotic resistance genes found in ST167 Escherichia coli strainsa
| Parameter | Result for E. coli strain: |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sanji | ECONIH6 | AR_0011 | AR_0014 | AR_0149 | AR_0150 | AR_0151 | AR_0162 | WCHEC005237 | FDAARGOS_434 | CRE1493 | CREC-532 | CREC-629 | Y5 | SCEC020007 | |
| No. of plasmids | 6 | 2 | 3 | 2 | 2 | 3 | 2 | 4 | 8 | 1 | 5 | 3 | 3 | 3 | 2 |
| Total no. of AR genesb | 32 (34) | 21 (22) | 12 (13) | 8 | 3 | 14 | 4 | 15 | 21 (28) | 15 (24) | 30 (36) | 19 (25) | 19 (23) | 25 (43) | 16 (24) |
| Chromosome-carried AR genes | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 6 | 12 (20) | 0 |
| Plasmid-carried AR genes | 28 | 21 (22) | 12 (13) | 8 | 3 | 14 | 4 | 15 | 21 (28) | 15 (24) | 30 (36) | 17 (19) | 17 | 21 (23) | 16 (24) |
| No. of IS26 elements on plasmids | 12 | 8 | 6 | 6 | 1 | 3 | 1 | 9 | 10 | 5 | 12 | 10 | 8 | 10 | 6 |
| No. of AR genes near IS26c | 24 | 16 | 12 | 8 | 0 | 12 | 2 | 13 | 8 | 24 | 25 | 15 | 8 | 21 | 22 |
| Presence of gene: | |||||||||||||||
| aac(3)-IIa | N | N | Y | Y | N | N | N | N | N | N | Y | N | N | N | N |
| aac(3)-IId | N | N | N | N | N | N | N | N | N | N | Y | Y | Y | Y | N |
| aac(3)-IVa | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| aac(3)*d | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| aac(6')Ib-cr | Y | N | Y | Y | N | N | N | N | Y | N | Y | N | N | Y | N |
| aadA1 | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| aadA2 | Y | Y | N | N | N | N | N | N | N | Y | Y | N | N | N | N |
| aadA5 | N | N | N | N | N | Y | N | N | N | Y | Y | Y | Y | Y | Y |
| aadA16 | N | N | N | N | N | N | N | N | Y | N | N | N | N | N | Y |
| aph(4)-Ia | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| aph(3′)-Ia | Y | N | N | N | N | N | N | N | N | N | N | N | N | Y | N |
| arr-3 | Y | N | N | N | N | N | N | N | Y | N | N | N | N | Y | N |
| blaCMY-42 | N | N | N | N | Y | Y | Y | N | N | N | N | N | N | Y | N |
| blaCTX-M-14 | Y | N | N | N | N | N | N | N | N | N | N | Y | Y | Y | N |
| blaCTX-M-15 | N | Y | Y | Y | N | N | N | Y | N | Y | Y | N | N | Y | N |
| blaCTX-M-55 | N | N | N | N | N | N | N | N | Y | N | N | Y | Y | N | N |
| blaNDM-5 | N | Y | N | N | N | Y | Y | N | Y | Y | Y | N | N | N | Y |
| blaNDM-7 | N | N | N | N | Y | N | N | Y | N | N | N | Y | Y | Y | N |
| blaOXA-1 | Y | Y | Y | Y | N | N | N | N | N | N | Y | N | N | Y | N |
| blaTEM-1A | N | N | N | N | N | N | N | N | N | N | Y | N | N | N | N |
| blaTEM-1B | N | N | N | N | N | Y | Y | Y | Y | N | N | Y | Y | N | Y |
| ble | N | Y | N | N | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y |
| catB3 | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| cmlA1 | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| dfrA12 | N | Y | N | N | N | N | N | N | N | Y | Y | N | N | N | Y |
| dfrA14 | N | Y | N | N | N | N | N | N | Y | N | N | N | N | N | N |
| dfrA17 | N | N | N | N | N | Y | N | N | N | Y | Y | Y | Y | Y | Y |
| dfrA27 | N | N | N | N | N | N | N | N | Y | N | N | N | N | Y | N |
| eamA | N | Y | Y | Y | N | Y | N | Y | Y | Y | Y | N | N | Y | Y |
| erm(B) | N | Y | N | N | N | N | N | Y | N | N | N | Y | Y | N | N |
| estX | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| floR_2 | Y | N | N | N | N | N | N | N | Y | N | Y | N | N | Y | N |
| fosA_14 | N | N | N | N | N | N | N | N | Y | N | N | N | N | N | N |
| glmM | Y | N | Y | N | N | N | N | N | N | N | N | N | N | N | N |
| mcr-1 | N | N | N | N | N | N | N | N | N | N | Y | N | N | N | N |
| mph(A) | Y | Y | N | N | N | Y | N | Y | N | Y | Y | Y | Y | Y | Y |
| mphR | Y | Y | N | N | N | Y | N | Y | N | Y | Y | Y | Y | Y | Y |
| mrx | Y | Y | N | N | N | Y | N | Y | N | Y | Y | Y | Y | Y | Y |
| nimC/nimA | N | N | N | N | N | N | N | N | N | N | Y | N | N | N | N |
| oqxA | Y | N | N | N | N | N | N | N | N | N | Y | N | N | N | N |
| oqxB | Y | N | N | N | N | N | N | N | N | N | Y | N | N | N | N |
| oqxR | Y | N | N | N | N | N | N | N | N | N | Y | N | N | N | N |
| psp | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| qacEd1 | Y | Y | N | N | N | Y | N | N | Y | Y | Y | Y | Y | Y | Y |
| qacI | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| qnrS1 | N | Y | N | N | N | N | N | Y | Y | N | N | N | N | N | N |
| rmtB | N | Y | N | N | N | N | N | N | Y | N | N | N | N | N | Y |
| strA | Y | Y | Y | N | N | N | N | Y | Y | N | Y | N | N | Y | N |
| strB | Y | Y | Y | N | N | N | N | Y | Y | N | Y | N | N | Y | N |
| sul1 | Y | Y | N | N | N | Y | N | N | Y | Y | Y | Y | Y | Y | Y |
| sul2 | Y | Y | Y | N | N | N | N | Y | Y | N | Y | N | N | Y | N |
| sul3 | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| tet(A) | Y | Y | Y | Y | N | Y | N | Y | Y | Y | Y | N | N | Y | Y |
| tet(B) | N | N | N | N | N | N | N | N | N | N | N | Y | Y | N | N |
| tetC | N | N | N | N | N | N | N | N | N | N | N | Y | Y | N | N |
| tetD | N | N | N | N | N | N | N | N | N | N | N | Y | Y | N | N |
| tet(M) | Y | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| tetR | Y | Y | Y | Y | N | Y | N | Y | Y | Y | Y | N | N | Y | Y |
| tetR(B) | N | N | N | N | N | N | N | N | N | N | N | Y | Y | N | N |
| tmrB | N | N | Y | Y | N | N | N | N | N | N | Y | Y | Y | N | N |
a
Y, yes (present); N, no (not present).
b
AR genes, antibiotic resistance genes, including resistance genes carried on both plasmids and chromosomes and their associated transcriptional regulators. Multiple copies of the same genes were counted only once each. Numbers in parentheses represent all copies of genes.
c
No. of AR genes near IS26, number of antibiotic resistance genes, including multiple copies of same gene, in a cluster within 20 kb of an IS26 element. Antibiotic genes found within 10 kb of each other were considered to be part of the same gene cluster.
d
A gene with a GNAT domain and overlapping with a transposase.