Table 3. Results of univariate and multivariate analyzes of the effect of number of recurrences on recurrence-free time–Landmark analysis.

			RECURRENCE FREE TIME
Landmark	Number of		HR (CI 95%)
	recurrences	Effectives	Univariate	Multivariate ƚ
3 YEARS	1	90	2.21 (1.39–3.51)	2.11 (1.28–3.49)
	2–3	80	4.94 (3.25–7.50)	4.72 (2.77–8.05)
	> = 4	15	3.13 (1.39–7.04)	2.63 (0.97–7.15)

Univariate and multivariate hazard ratios were estimated using cox model.

ƚ Adjusted on age, sex, smoking, previous treatment and stratified on the EORTC risk score (low versus moderate/high) at baseline.