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. 2019 Feb 27;14(2):e0212732. doi: 10.1371/journal.pone.0212732

Fig 2. IL33, MIPs, Glutamine Synthetase (GS) and Nestin mRNA expression in Reeler retinas.

Fig 2

Total RNA was extracted from not pooled retinas and used to generate cDNA for real time PCR analysis. (A) Histogram showing a downregulation for MIP3α and MIP3β mRNAs and an upregulation for IL-33 mRNA in Reeler retinas, as compared to WT ones. (B) Histogram showing mRNA expression changes for GS and Nestin at all time-points investigated, representative of a local Müller activation. Significant differences between subgroups are shown as *p<0.05 and **p<0.01; ANOVA-REST coupled analysis). Data are 2log gene expression (mean±SEM, Reeler vs. WT).