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. 2019 Feb 27;14(2):e0212732. doi: 10.1371/journal.pone.0212732

Table 2. Sketch of significant inflammatory/profibrogenic mediators in p28 Reeler vitreous.

Mediator Function FC (Sign) Cell origin in the retina [ref]
βNGF Growth factor 7.23 (*) all cells [1,2,50]
IL33 Pro-inflammatory and pro-fibrogenic cytokine 4.96 (*) glial cells [35,40]
TIMP1 Metalloproteinase inhibitor 4.79 (*) glial cells [52]

Values obtained from protein chip array showing the fold changes (FC) in the expression of some inflammatory/profibrogenic mediators at p28 Reeler retina as compared to WT. Significant values (Sign) are labeled by asterisk (*, p<0.05) or ns (not significant).