Table 2.
Amniotic Fluid Cytokine Levels
| Study Groupa | Cytokine Level, Median (IQR), ng/mL |
||||||
|---|---|---|---|---|---|---|---|
| IL-1β | IL-6 | CXCL8 | TNF-α | CCL2 | IL-1ra | IL-10 | |
| Control (n = 5) | 0.4 (0.01–0.4) | 396 (301–893) | 138 (67–946) | 0.1 (0.1–21) | 954 (521–1152) | 208 (142–289) | 0.1 (0.1–3) |
| U. parvum infected, 3 d (n = 5) | 0.4 (0.01–0.4) | 360 (210–859) | 147 (119–700) | 0.1 (0.1–6.4) | 673 (512–878) | 90 (27–213) | 0.1 (0.1–0.1) |
| U. parvum infected, 7 d (n = 5) | 0.6 (0.6–1.2) | 532 (426–1006) | 635 (323–1486) | 2.5 (5.8–55.9) | 2231 (1416–2541)b | 257 (172–644) | 0.1 (0.1–27.6) |
Abbreviations: IL-1β, interleukin 1β; IL-1ra, interleukin 1ra; IL-6, interleukin 6; IL-10, interleukin 10; IQR, interquartile range; TNF, tumor necrosis factor; U. parvum, Ureaplasma parvum.
aU. parvum (1 × 107 colony-forming units) was given via intra-amniotic injection.
bP < .05 vs control.