Figure 2.

Representative example of 2-dimensional echocardiography (A and B), speckle tracking imaging (C), cardiac MRI (D), and resting electrocardiogram (E) in a patient with reported hemizygous -10 C>T single nucleotide polymorphisms (patient no. 12). Echocardiography and cardiac MRI revealed mild left ventricular hypertrophy (interventricular septal wall thickness is 12 mm). Although global systolic function and diastolic function remain normal, a significantly reduced strain rate and strain at the septal basal segment is evidenced by speckle tracking hinting on a myocardial pathology. MRI = magnetic resonance imaging.