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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: J Thromb Thrombolysis. 2019 Feb;47(2):174–178. doi: 10.1007/s11239-018-1782-3

Figure 1. Platelet count declines following TAVR in every generation of valve and is mildly blunted when conscious sedation is used.

Figure 1.

(A) Mean and standard deviation of platelet counts in cohorts undergoing transfemoral access TAVR (n = 22 for Sapien, n= 20 for Sapien XT, n = 17 for CoreValve, and n = 86 for Sapien 3). No significant difference was detected in platelet decline between any of the valve types (p = 0.622) as determined using a two way repeated measures ANOVA. (B) Mean and standard deviation of platelet counts in cohorts undergoing transfemoral access TAVR with general anesthesia (n = 90) or conscious sedation (n= 65). There was a significant difference in platelet decline between the sedation methods (p = 0.026) as determined using a two way repeated measures ANOVA. (C) Pearson correlation analysis was conducted between baseline platelet count and the change of platelet count observed post-operatively.