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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):523–529. doi: 10.1161/ATVBAHA.118.312267

Table 2.

Lp(a)-related risk of carotid plaque at baseline* was assessed in 5,155 Multi-Ethnic Study of Atherosclerosis participants stratified by race/ethnicity.

Black
N=1393
Caucasian
N=1986
Chinese American
N=620
Hispanic
N=1156
per Lp(a) log unit 1.02 (0.80 − 1.07) 1.05 (1.03 − 1.08)
<0.001
1.06 (0.97 − 1.16) 1.04 (0.99 − 1.09)
0.10
Lp(a)≥ 30 mg/dL 1.03 (0.94 − 1.13) 1.16 (1.09 − 1.24)
<0.001
1.14 (0.91 − 1.41) 1.12 (0.99 − 1.26)
0.07
Lp(a)≥ 50 mg/dL 1.05 (0.96 − 1.15) 1.20 (1.12 − 1.28)
<0.001
1.10 (0.82 − 1.47) 1.13 (0.98 − 1.30)
0.11

Risk ratios and 95% confidence intervals are shown, p-values where significant or approaching significance. Covariate adjustments were made for age, sex, systolic blood pressure, hypertension and lipid lowering medication use, total cholesterol, HDL-C, diabetes, and smoking status. Race-interactions were tested between racial/ethnic groups. Individuals with missing covariate data were excluded. Definitions: Lp(a)=lipoprotein(a); diabetes=treated and untreated cases; HDL-C=high density lipoprotein-cholesterol; smoking status=current, former, never

*

Carotid plaque is modeled as a logistical variable (0 or 1); absent or present at baseline

Significantly different than Black participants (p for interaction<0.10)