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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):523–529. doi: 10.1161/ATVBAHA.118.312267

Table 4.

Lp(a)-related risk of carotid plaque progression* over a median 9.4 year period in 3,380 Multi-Ethnic Study of Atherosclerosis participants stratified by race/ethnicity.

Black
N=885
Caucasian
N=1326
Chinese American
N=435
Hispanic
N=734
per Lp(a) log unit 1.04 (0.98 − 1.10) 1.02 (0.99 − 1.05) 1.01 (0.94 − 1.09) 0.99 (0.95 − 1.03)
Lp(a)≥ 30 mg/dL 1.02 (0.91 − 1.15) 1.06 (0.97 − 1.17) 0.93 (0.76 − 1.12) 1.02 (0.90 − 1.15)
Lp(a)≥ 50 mg/dL 1.05 (0.93 − 1.18) 1.12 (1.01 − 1.24)
0.03
0.97 (0.77 − 1.21) 1.09 (0.95 − 1.25)

Risk ratios and 95% confidence intervals are shown, p-values where significant. Covariate adjustments were made for age, sex, systolic blood pressure, hypertension and lipid lowering medication use, total cholesterol, HDL-C, diabetes, and smoking status. Race-interactions were tested between racial/ethnic groups. Definitions: Lp(a)=lipoprotein(a); diabetes=treated and untreated cases; HDL-C=high density lipoprotein-cholesterol; smoking status=current, former, never

*

Carotid plaque progression was modeled as a logistical variable (0 or 1); progression was considered to have occurred when a new plaque developed after baseline

No significant race-interactions were observed