Table 5.

Prospective associations between Lp(a) levels and carotid plaque score^* following a median period of 9.4 years in 3,380 Multi-Ethnic Study of Atherosclerosis participants stratified by race/ethnicity.

	Black N=885	Caucasian N=1326	Chinese American N=435	Hispanic N=734
per Lp(a) log unit	0.05 (−0.8 − 0.18)	0.12 (0.05 − 0.20) 0.001	0.04 (−0.12 − 0.20)	0.07 (−0.04 − 0.17)
Lp(a)≥ 30 mg/dL	0.04 (−0.21 − 0.29)	0.38 (0.16 − 0.61)† 0.001	−0.21 (−0.64 − 0.22)**	0.20 (−0.10 − 0.51)
Lp(a)≥ 50 mg/dL	0.06 (−0.20 − 0.32)	0.51 (0.25 − 0.77)† <0.001	−0.04 (−0.59 − 0.50)	0.35 (−0.03 − 0.73)

Regression coefficients and 95% confidence intervals are shown, p-values where significant or approaching significance. Covariate adjustments were made for age, sex, systolic blood pressure, hypertension and lipid lowering medication use, total cholesterol, HDL-C, diabetes, and smoking status. Race-interactions were tested among racial/ethnic groups

^*Modeled as an ordinal variable with plaque score values from 0 to 12

^†Significantly different than Black participants (p for interaction<0.10)

^**Significantly different than Caucasian participants (p for interaction<0.10)

Definitions: Lp(a)=lipoprotein(a); diabetes=treated and untreated cases; HDL-C=high density lipoprotein-cholesterol; smoking status=current, former, never