Table 1:

Characteristics of Patients with ESRD due to Lupus Nephritis in the United States between 1995–2014

Year of Initial ESRD	1995–1999	2000–2004	2005–2009	2010–2014
Number of Cases	4,861	5,413	5,540	5,160
Annual Incidence (95% CI)*	3.6 (3.4–3.8)	3.8 (3.6–4.0)	3.7 (3.5–3.9)	3.3 (3.1–3.5)
Demographics
Age (Mean, SD)	40.1 (15.3)	39.9 (15.5)	39.4 (15.4)	40.5 (15.7)
Sex (Female %)	81.9	81.6	81.8	81.7
Race (%)
White	42.4	41.8	41.8	43.3
African American	45.9	48.0	50.1	48.6
Asian	3.5	3.3	5.1	5.8
Other	8.4	6.9	3	2.3
Hispanic	15.9	17.8	19.6	19.4
BMI (kg/m2, SD)	24.8 (6.7)	26.1 (7.0)	26.8 (7.4)	27.3 (7.8)
Region† (%)
Northeast	13.8	13.5	13.0	13.4
Midwest	19.2	18.8	17.8	17.1
South	41.6	43.0	45.6	44.6
West	20.1	19.9	19.1	20.7
Comorbid Conditions (%)
Diabetes	5.9	3.9	9.4	9.7
Hypertension	69.9	75.9	82.7	85.7
Coronary Artery Disease	6.8	7.3	5.2	4.8
Congestive Heart Failure	16.3	15.2	13.8	13.7
Peripheral Vascular Disease	3.0	3.5	3.2	2.6
Stroke or TIA	5.0	5.3	5.2	5.2
Current Smoking	3.7	4.0	4.2	4.3
History of Malignancy	1.3	1.5	1.5	2.0
Initial ESRD Treatment (%)
Transplant	2.2	3.0	3.8	4.4
Hemodialysis	83.3	86.4	86.3	82.6
Peritoneal Dialysis	14.5	10.6	9.9	12.9

BMI, body mass index; TIA, Transient Ischemic Attack

^*/1,000,000 US Population;

^†These four regions capture all of the United States. Patients from Puerto Rico, other US territories, and foreign countries were excluded from these analyses since US population census estimates do not include these individuals.