Table 3:

Temporal Trends in Risk of Death in ESRD due to Lupus Nephritis (1995–2014) Stratified by Race/Ethnicity

Year of ESRD Initiation	N	Follow-up Time (PY)	Number of Deaths	Unadjusted HR (95% CI)	Age-, Sex-, BMI-Adjusted HR (95% CI)	Multivariate Adjusted† HR (95% CI)
White
1995–1999	2,063	4,090	490	1.00 (ref)	1.00 (ref)	1.00 (ref)
2000–2004	2,265	4,521	548	1.02 (0.90–1.17)	1.04 (0.91–1.19)	1.08 (0.95–1.23)
2005–2009	2,317	5,008	452	0.77 (0.67–0.89)	0.80 (0.70–0.92)	0.93 (0.80–1.06)
2010–2014	2,236	4,948	356	0.62 (0.54–0.72)	0.62 (0.53–0.72)	0.68 (0.58–0.78)
P-for-trend				<0.001	<0.001	<0.001
African American
1995–1999	2,231	4,402	497	1.00 (ref)	1.00 (ref)	1.00 (ref)
2000–2004	2,599	5,197	573	1.03 (0.90–1.17)	1.03 (0.90–1.17)	1.07 (0.94–1.23)
2005–2009	2,777	5,879	555	0.88 (0.77–0.99)	0.88 (0.77–0.99)	0.87 (0.76–1.00)
2010–2014	2,505	5,683	380	0.63 (0.55–0.73)	0.62 (0.54–0.72)	0.67 (0.57–0.78)
P-for-trend				<0.001	<0.001	<0.001
Asian
1995–1999	170	397	24	1.00 (ref)	1.00 (ref)	1.00 (ref)
2000–2004	177	408	22	0.88 (0.46–1.68)	0.97 (0.51–1.86)	1.22 (0.63–2.37)
2005–2009	285	671	33	0.87 (0.49–1.57)	0.94 (0.52–1.69)	1.08 (0.59–1.99)
2010–2014	301	717	29	0.72 (0.40–1.32)	0.75 (0.41–1.37)	0.90 (0.48–1.68)
P-for-trend				0.20	0.31	0.56
Hispanic
1995–1999	773	1,632	126	1.00 (ref)	1.00 (ref)	1.00 (ref)
2000–2004	965	2,131	152	0.93 (0.72–1.20)	0.96 (0.75–1.24)	0.99 (0.76–1.28)
2005–2009	1,085	2,493	128	0.70 (0.52–0.88)	0.69 (0.53–0.89)	0.69 (0.52–0.90)
2010–2014	1,003	2,431	89	0.48 (0.36–0.64)	0.47 (0.35–0.63)	0.51 (0.38–0.69)
P-for-trend				<0.001	<0.001	<0.001

^†Adjusted for age, sex, BMI, diabetes, hypertension, current smoker, coronary artery disease, congestive heart failure, cerebrovascular accident, region, and first modality