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. Author manuscript; available in PMC: 2019 Aug 27.
Published in final edited form as: Artif Cells Nanomed Biotechnol. 2018 Aug 27;46(SUP3):S434–S447. doi: 10.1080/21691401.2018.1499660

Figure 2.

Figure 2.

Physical properties of physical cross-linked collagen hydrogels vary with collagen concentration with limited tunability. (a) Gelation time decreased and shear storage modulus (G’) increased with increasing collagen concentration. (b) Swelling properties decreased with increasing collagen concentration. (c) Diffusion properties of 3D collagen hydrogel remains the same with increasing collagen concentration. (d-f) Mesh density increased linearly with collagen concentration as shown in (d) 3D confocal microscopy images. (e-f) Summarized data of 0.15, 0.3, and 0.6 % collagen hydrogels. P-values less than 0.1 and 0.001 were considered statistically significant and were labeled * and *** compared with the 0.15 % collagen hydrogel.