Figure 3.

Tunable physical properties of chemical cross-linked collagen-Ph hydrogels varied with HRP, H₂O₂, and collagen-Ph concentration. (a) Gelation time was adjustable by HRP concentration. (b) Shear storage modulus (G’) increased with increasing collagen concentration and H₂O₂ concentration with a suitable amount of HRP. (c) Swelling properties remained constant with increasing collagen-Ph concentration or increasing G’. (d) Diffusion properties of collagen-Ph hydrogel as a function of collagen-Ph concentration and G’. Diffusion distances are larger than 3 mm for 0.15 % collagen-Ph hydrogels with G’=50 and 100 Pa, whereas others are below 2 mm. P-values less than 0.01 and 0.001 were considered statistically significant and were labeled ** and *** compared with the 0.15% collagen-Ph hydrogel with the same G’. P-values less than 0.1 were considered statistically significant and were labeled # compared with the collagen-Ph hydrogel with G’ of 50 Pa at the same concentration.