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. 2018 Dec 19;47(4):1605–1614. doi: 10.1093/nar/gky1263

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Runtime comparison between WISECONDOR and WisecondorX. Minutes are presented in logarithmic scale. Timing covered the ‘bam to result’ principle (meaning the combination of the convert and test (WISECONDOR) or predict (WisecondorX) functions). Despite not being analyzed by this validation set, WISECONDOR exceeds a mean runtime of 24 h for resolutions of 15 kb (supposed exponential complexity for the test function), whereas WisecondorX barely increased with 2 min (supposed linear complexity for the predict function). The increased runtime in WISECONDOR is caused by the iterative Stouffer's z-score procedure.