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. 2019 Jan 9;47(4):1950–1963. doi: 10.1093/nar/gky1309

Figure 7.

Figure 7.

Surface view of the Redβ CTD showing the binding site for λ Exo, which may overlap with a binding site for SSB-Ct. (A) Mapping of mutational data. The labeled residues constitute the surface of the CTD that contacts λ Exo in the complex. Residues mutated in this study are shown in cyan if the mutation disrupted ssDNA recombination, or magenta if not. The residues in cyan thus map out a putative site for binding SSB-Ct. Notice the deep pocket, to which Phe-94 of λ Exo binds, and to which Phe-177 of the SSB C-tail could putatively bind. (B) Surface electrostatics. The surface is colored red for negative and blue for positive (±75 kBT). The positive charge around Lys-253 binds to the C-terminal end of helix E of λ Exo, and putatively to the C-terminus of SSB.