Table 2.

Univariate and multivariate Cox proportional methods.

			Univariate		FDR	Multivariate*
Gene and rsID	Genotype	N (%)	P-value	HR (95% CI)	P-value	P-value	HR (95% CI)
ERCC1 (C8092A)	CC	97 (54)		1			1
rs3212986	CA	66 (37)	0.70	0.92 (0.62–1.38)	>1	0.56	0.88 (0.59–1.33)
	AA	17 (9)	0.02	1.93 (1.09–3.40)	0.03	0.06	1.75 (0.98–3.11)
	CC+CA	163 (91)		1			1
	AA	17 (9)	0.01	1.41 (1.08–1.85)	0.02	0.02	1.80 (1.06–3.18)
ERCC2/XPD (Asp312Asn)	GG	57 (32)		1			1
rs1799793	GA	100 (56)	0.008	1.8 (1.16–2.84)	0.02	0.02	1.74 (1.11–2.72)
	AA	23 (12)	0.008	2.3 (1.24–4.16)	0.03	0.01	2.19 (1.19–4.03)
	GG	57 (32)		1			1
	GA+AA	123 (68)	0.004	1.89 (1.22–2.92)	0.04	0.007	1.81 (1.17–2.80)

^*Corrected for histological type, clinical stage, treatment, and age at diagnosis.