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. 2019 Feb 21;6:35. doi: 10.3389/fvets.2019.00035

Table 2.

Summary of atypical porcine pestivirus studies.

Year Country Serology Strength(s) References
2015 United States + Virus discovered by next-generation sequencing (9)
2016 United States Experimental inoculation in fetuses (45 and 62 days of gestation) (10)
2016 Netherlands Experimental intramuscular inoculation (32 days of gestation) (2)
2016 Germany Detection of APPV genome by fluorescent in-situ hybridization/Detection in adult domestic pigs/Virus isolation was attempted (failed) (15)
2016 Germany First indication of a cell culture isolate is provided/Detection in adult domestic pigs (16)
2017 Austria + Persistent infection condition was suggested/Virus isolation (inefficient) (3)
2017 China Viral strains showed highly genetic diversity (30)
2017 China Suggested APPV origin and dissemination/Virus isolation attempted (failed) (22)
2017 Great Britain First detection in the country (28)
2017 Spain + Retrospective study (virus was identified at least since 1997)/Detection in adult domestic pigs (21)
2017 Switzerland/China/Great Britain/Germany/Italy/Republic of Serbia/Taiwan + Geographically wide distribution of genetically highly variable APPV and high APPV genome detection (29)
2017 South Korea First detection in the country (23)
2018 China Suggested a novel APPV strain in China (31)
2018 Brazil First detection in Brazil/Formalin-fixed paraffin-embedded samples were used (4)
2018 Brazil Sequencing and analysis of the partial NS5B gene (24)
2018 Brazil High lethality and coinfection with porcine teschovirus (PTV) (25)
2018 United States Detection in semen, preputial swabs, and preputial fluids from boar studs (32)
2018 China Identification and characterization of two possible strains (33)
2018 Germany/Republic of Servia + First detection in wild boars/Detection of APPV-antibodies in wild boars from the Republic of Serbia (34)
2018 Hungary + First detection in this country/Distinct lineages were reported, suggesting multiple introduction events of the virus (27)
2018 Canada First detection in the country (26)
2018 Spain Detection in wild boars/Low prevalence (35)
2018 Brazil APPV-associated with pathological lesions (36)