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. 2019 Feb 21;10:137. doi: 10.3389/fphar.2019.00137

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Copyright © 2019 Wu, Zhang, Huang, Gu, Zhou, Yin and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inverse correlation between miR-409-3p and ZEB1 mRNA expression levels in OS tissues. (A) RT-qPCR analysis showing that ZEB1 mRNA levels were increased in OS tissues. (B) Spearman’s correlation analysis of the association between miR-409-3p and ZEB1 mRNA in OS tissues. (C) Expressions of miR-409-3p and ZEB1 mRNA in cell lines. miR-409, microRNA-409-3p. OS, osteosarcoma. ZEB1, Zinc-finger E-box-binding Homeobox-1. mRNA, message RNA. ^∗P < 0.05, ^∗∗P < 0.01 compared with the control group.