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. 2019 Feb 27;9:2946. doi: 10.1038/s41598-019-39897-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Global PDF results between the MIN_DTE (blue) and the MAX_DTE (red) VADs. The main mode of the MAX_DTE appeared to have wider distribution and located at the higher SA range, compared with the MIN_DTE main mode. Higher platelet distribution was also found in the tail region (i.e., SA >50 dyne·s/cm²) of the MAX_DTE, which represented more platelets traverse through would experience higher levels of shear stress (inset).