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. 2019 Feb 27;10(3):203. doi: 10.1038/s41419-018-1289-z

Fig. 1. AKT inhibition significantly decreases the axon regeneration induced by PTEN deletion.

Fig. 1

a Confocal images of ON longitudinal sections showing regenerating fibers labeled with CTB-Alexa 488 2 weeks after ON crush. Scale bar, 100 µm. *Crush site. b Quantification of regenerating fibers at different distances distal to the lesion site. Data are presented as means ± s.e.m., n = 8–10. **p < 0.01, ***p < 0.001, ****p < 0.0001 versus Pten KO alone. One-way ANOVA with Bonferroni’s post hoc test. ANOVA, analysis of variance; CTB, cholera toxin β; ON, optic nerve