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. 2019 Feb 27;9:2965. doi: 10.1038/s41598-019-39182-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Heat maps of an unsupervised hierarchical clustering of proteins with fold changes (>2 and <0.5). The colors in the map displayed the relative expression values. Green indicated the lowest expression, black for the intermediate expression, and red for the highest expression. The numerical values gave the actual values on a log2 scale, which were associated with each color. The color scale bar is shown at the lower left corner. (A) KC cone epithelium and stroma were compared to normal corneal samples. (B) KC non-cone epithelium and stroma were compared to normal corneal samples.