Table 2.

Average IC₅₀ values for top compounds with selective inhibition against copper-only SOD5 versus Cu,Zn-SOD1

Compound	Average IC50 ± S.E.a
	Copper-only SOD5	Cu,Zn-SOD1
Diethyldithiocarbamic acid	100 ± 6 nm	NDb
Ammonium tetrathiomolybdate	300 ± 69 nm	17 ± 1.4 μm
Pyrithione Zinc	400 ± 44 nm	ND
Clioquinol	723 ± 128 nm	ND
Chloroxine	816 ± 150 nm	ND
Bathophenanthroline sulfonic acid	30 ± 1.6 μm	ND
Ciclopirox	30 ± 18 μm	ND

^a Results are averages of nine samples over three experimental trials.

^b ND, not defined; IC₅₀ for Cu,Zn-SOD was not defined due to insufficient or absent inhibition of enzyme activity over the dose range of compounds tested (0.04–90 μm).