Figure 8.
TPG-1 dramatically inhibited the oncogenicity of mouse hepatoma H22 cells in Kunming mice. A, hepatoma H22-bearing Kunming mice were treated with TPG-1 (i.p., 60 mg/kg, once daily) or 5-FU (i.p., 30 mg/kg, three times per week). B, body weight of the Kunming mice during drug treatment. C, H&E staining of major organs from Kunming mice treated with or without TPG-1. Scale bar, 50 μm. D, H&E staining and immunohistochemical analysis of tumor tissues from Kunming mice treated with or without TPG-1. Scale bar, 50 μm (left) or 200 μm (right). **, p < 0.01; ***, p < 0.001. Error bars, confidence interval.