Table 2.
OS | DFS | |||||||
---|---|---|---|---|---|---|---|---|
HR (95% CI)[Link] | p [Link] | HR (95% CI)[Link] | p [Link] | HR (95% CI)[Link] | p [Link] | HR (95% CI)[Link] | p [Link] | |
AGER | 0.640 (0.476–0.860) | 0.003 | 0.558 (0.385–0.810) | 0.002 | 0.627 (0.468–0.839) | 0.002 | 0.514 (0.357–0.740) | 0.000 |
CCNB1 | 1.711 (1.271–2.304) | 0.000 | 1.701 (1.164–2.485) | 0.006 | 1.536 (1.147–2.056) | 0.004 | 1.763 (1.217–2.553) | 0.003 |
CENPU | 1.549 (1.153–2.081) | 0.004 | 1.631 (1.103–2.414) | 0.014 | 1.360 (1.017–1.818) | 0.038 | 1.541 (1.055–2.252) | 0.025 |
CLIC5 | 0.729 (0.544–0.977) | 0.034 | 0.615 (0.422–0.896) | 0.011 | 0.728 (0.545–0.972) | 0.032 | 0.600 (0.416–0.867) | 0.006 |
COL11A1 | 1.376 (1.024–1.848) | 0.034 | 1.347 (0.930–1.952) | 0.115 | ||||
FAM107A | 0.742 (0.553–0.995) | 0.046 | 0.663 (0.458–0.961) | 0.030 | ||||
FAM189A2 | 0.626 (0.466–0.841) | 0.002 | 0.625 (0.430–0.908) | 0.014 | 0.722 (0.540–0.964) | 0.027 | 0.612 (0.425–0.883) | 0.009 |
GOLM1 | 1.700 (1.267–2.282) | 0.000 | 1.409 (0.977–2.032) | 0.067 | 1.648 (1.232–2.206) | 0.001 | 1.260 (0.881–1.801) | 0.206 |
SLIT3 | 0.635 (0.472–0.854) | 0.003 | 0.628 (0.431–0.915) | 0.015 | ||||
TMEM106B | 1.361 (1.014–1.827) | 0.040 | 1.251 (0.869–1.800) | 0.228 | 1.603 (1.195–2.150) | 0.002 | 1.385 (0.968–1.983) | 0.075 |
CI: confidence interval; DFS: disease‐free survival; HR: hazard ratio; OS: overall survival.
Univariate Cox proportional hazard model.
Multivariate Cox proportional hazard model by adjusting for age (<65 and ≥65), gender (male and female), smoking (<40 and ≥40 pack‐year).