Table 1.
Growth Promoters Affecting Reduction/Oxidation Gene Activation
| Growth promoter | Associated redox gene | References |
|---|---|---|
| BRAF | SOD3 | (33, 196) |
| cABL | NOX5 | (86) |
| E1A | NOX4 | (34) |
| EGF | SOD1 | (157) |
| EGFR | NOX3, NOX4 | (170, 172, 203) |
| FLT-ITD | NOX4 | (154, 155) |
| IGF | SOD1 | (157) |
| MCF7 | SOD1 | (272) |
| MCF-10A | SOD1 | (272) |
| MDA-MB157 | SOD1 | (272) |
| MDA-MB-231 | SOD1 | (272) |
| PDGF | NOX1, NOX5 | (153, 187) |
| PI3K | NADPH oxidase complex activation | (139) |
| PKA | NOX1 | (71, 181, 388) |
| PKC | NOX1, NOX2 | (107, 332, 388) |
| RAS | NOX1, NOX4, SOD2, SOD3 | (5, 34, 39, 188, 189, 195, 196, 272) |
| RGS4 | SOD3 | (189) |
| SRC family | NOX1–5, SOD3 | (45, 56, 104, 106, 170, 172, 322) |
EGF, epidermal growth factor; FLT-ITD, FMS-like tyrosine kinase with internal tandem duplication; IGF, insulin growth factor; PDGF, platelet-derived growth factor; PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase; PKA, protein kinase A; PKC, protein kinase C; redox, reduction/oxidation; RGS4, regulator of G protein signaling 4; SOD, superoxide dismutase.