Table 2.
Top 20 Downregulated Genes / mRNAs in the Peripheral Blood Cells of Patients With 3 Types of Cancer After the First 2 Gy Fraction of Radiotherapy.
| Cervical Cancer | Nasopharyngeal Cancer | Tongue Cancer | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Accession | Symbol | Log2 (Fold) | P Value | Accession | Symbol | Log2 (Fold) | P Value | Accession | Symbol | Log2 (Fold) | P Value |
| NM_002165.3 | ID1 | −6.523 | 4.84E-176 | NM_001001437.3 | CCL3L3 | −4.507 | 8.48E-09 | NM_006588.3 | SULT1C4 | −3.889 | .000158 |
| NM_001114134.1 | EPB42 | −5.1923 | 3.68E-10 | NM_006121.3 | KRT1 | −4.419 | 2.71E-08 | NM_002124.3 | HLA-DRB1 | −3.675 | 1.42E-177 |
| NM_003214.3 | TEAD3 | −4.337 | 1.38E-05 | NM_197975.2 | BTNL3 | −3.943 | 1.89E-20 | NM_001306130.1 | FN1 | −3.371 | 6.52E-51 |
| NM_001167600.2 | NEU4 | -4.192 | 4.67E-05 | NM_015585.3 | CFAP61 | −3.741 | 2.70E-05 | NM_001102614.1 | SLC35G6 | −3.059 | 1.23E-07 |
| NM_001993.4 | F3 | −4.114 | 8.55E-05 | NM_007058.3 | CAPN11 | −3.589 | 8.39E-05 | NM_001005407.1 | CACNA1H | −3.059 | .000243 |
| NM_001945.2 | HBEGF | −4.019 | 3.03E-162 | NM_002777.3 | PRTN3 | −3.589 | 8.39E-05 | NM_001302690.1 | APOE | −2.866 | 7.83E-12 |
| NM_001318898.1 | FHL2 | −3.944 | 1.35E-07 | NM_001143824.1 | SLC38A4 | −3.589 | 8.39E-05 | NM_054034.2 | FN1 | −2.741 | 1.05E-11 |
| NM_003382.4 | VIPR2 | −3.944 | .000285 | NM_001330199.1 | SCUBE2 | −3.589 | 8.39E-05 | NM_138731.6 | MIPOL1 | −2.696 | .000174 |
| NM_001142966.1 | FHL2 | −3.645 | 1.35E-07 | NM_173615.4 | VWA3A | −3.589 | 8.39E-05 | NM_017878.1 | HRASLS2 | −2.696 | 9.30E-07 |
| NM_006783.4 | GREB1L | −3.599 | 4.65E-06 | NM_001170690.1 | SCUBE2 | −3.589 | 8.39E-05 | NM_030916.2 | NECTIN4 | −2.644 | 2.20E-05 |
| NM_001265594.1 | PLEKHG5 | −3.469 | 2.65E-05 | NM_001272037.1 | TSPEAR | −3.419 | .000258 | NM_001164444.1 | CBY3 | −2.412 | .000201 |
| NM_198714.1 | PTGER3 | −3.359 | 8.02E-07 | NM_001286056.1 | CNN3 | −3.419 | 1.86E-07 | NM_001270601.1 | ASCL5 | −2.412 | .000201 |
| NM_198404.2 | KCTD4 | −3.337 | 8.34E-05 | NM_001077621.1 | VPS37D | −3.326 | 5.62E-07 | NM_144706.3 | C2orf15 | −2.211 | .000216 |
| NM_020902.1 | GJB6 | −3.266 | 4.60E-10 | NM_001330142.1 | C10orf82 | −3.326 | 5.62E-07 | NM_001166292.1 | PTCH2 | −2.024 | 4.42E-52 |
| NM_001135171.1 | CAMSAP3 | −3.266 | 2.49E-06 | NM_014629.3 | ARHGEF10 | −3.127 | 1.15E-36 | NM_001161661.1 | WWC1 | −1.751 | 4.24E-05 |
| NM_001080429.2 | C1QTNF7 | −3.266 | .000147 | NM_001097622.1 | OCM | −3.119 | 5.06E-06 | NM_001287254.1 | ZNF596 | −1.685 | 2.53E-07 |
| NM_001286733.1 | GRTP1 | −3.192 | .000259 | NM_001329140.1 | PTPRF | −3.063 | 2.64E-10 | NM_183065.2 | TMEM107 | −1.557 | 1.52E-99 |
| NM_173354.4 | SIK1 | −3.125 | 2.18E-69 | NM_001657.3 | AREG | −3.004 | 1.49E-47 | NM_000020.2 | ACVRL1 | −1.538 | 6.98E-07 |
| NM_001165033.1 | RNF182 | −3.114 | 4.11E-07 | NM_001288563.1 | WDR63 | −2.942 | 2.26E-09 | NM_004794.2 | RAB33A | −1.537 | 1.12E-12 |
| NM_006497.3 | HIC1 | −3.082 | 1.73E-59 | NM_005434.4 | MALL | −2.922 | 3.07E-07 | NM_015345.3 | DAAM2 | −1.393 | 7.21E-16 |
Abbreviation: mRNA, messenger RNA.