Table 1. Amifostine (AMF) prevented 5-fluorouracil (5-FU)-associated macroscopic and microscopic injury.

Groups	Macroscopic scores	Microscopic scores
Saline	0 (0–0)	0 (0–0)
Scratch	1 (1–3)	2 (0–3)
5-FU + Saline	5 (3–5)*	3 (2–3)*
5-FU + AMF 12.5 mg/kg	3.5 (1–5)	2 (0–3)#
5-FU + AMF 25 mg/kg	2 (1–4)#	2.5 (1–3)

Data are reported as median and range of at least six samples. *P<0.05 vs saline group. ^#P<0.05 vs 5-FU group. Data were analyzed by Kruskal-Wallis and Dunn's tests.