Figure 1.

Global path length differences within multiple sclerosis (MS) groups after correction for connectivity density. Degree and connectivity density were lower in cognitively impaired MS patients (MS-CI) compared to the cognitively preserved group (MS-CP). To minimize the influence of the number of connections in the other network parameters, we applied an additional correction for the percentage of connections (i.e. connectivity density). After this correction, the standardized residual path length values were lower in MS-CI, and similar to the relationship observed for λ (i.e. characteristic path length normalized to path length values of 20 random graphs).