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. 2019 Feb 28;19:183. doi: 10.1186/s12885-019-5322-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — The effect of VEGFR2 on VTN expression. a & b Real-time PCR and Western blot analysis of relative levels of VTN in MKN-45 cells after VEGFR2 knockdown. c & d Real-time PCR and Western blot analysis of relative levels of VTN in SCH cells after VEGFR2 overexpression. e & f Real-time PCR and Western blot analysis of relative levels of VTN in a panel of gastric cancer cell lines and immortalized normal human gastric mucosal epithelial cell line GES-1. g & h IHC staining analysis of VTN in MKN-45 xenograft tumors. i & j IHC staining analysis of VTN in SCH xenograft tumors. k Representative images of anti-VTN staining in human gastric cancer tissues. l Relationship between expressions of VEGFR2 and VTN in human gastric cancer tissues. **P < 0.01, significant differences vs. the respective control groups