Table 2.

Sensitivity of Pa strains against selected antibiotics measured by E-tests.

			MIC Breakpoint (mg/L)		PA14 SurA			ID72 SurA			PA14 BamB
			S ≤	R >	PA14 WT	PA14 surA	PA14 surA SurA+	ID72	ID72 surA	ID72 surA SurA+	PA14 WT	PA14 bamB	PA14 bamB BamB+
Penicillins	AMS	Ampicillin-sulbactam	–	–	>256	24	>256	>256	>256	>256	>256	32	>256
	PIT	Piperacillin-tazobactam	16	16	6	3	6	>256	<256	>256	6	2	6
	TIL	Ticarcillin-clavulanate	16	16	32	6	24	>256	64	>256	32	12	192
Carbapenems	DOR	Doripenem	1	2	0.25	0.38	0.38	>32	>32	>32	0.25	0.25	0.5
	MER	Meropenem	2	8	0.38	0.75	0.5	>32	>32	>32	0.38	0.5	1.5
Cephalosporins	CTA	Cefotaxime	–	–	16	8	16	>256	>256	>256	16	8	32
	CEP	Cefepime	8	8	0.75	0.25	0.75	>32	3	> 32	0.75	0.38	0.5
	CTZ	Ceftazidime	8	8	2	0.5	1	>256	8	64	2	0.38	1.5
Fluoroquinolones	LEV	Levofloxacin	1	1	0.38	0.094	0.38	1.5	0.064	0.75	0.38	0.25	0.38
	CIP	Ciprofloxacin	0.5	0.5	0.19	0.038	0.094	0.38	0.064	0.125	0.19	0.064	0.19
	FOS	Fosfomycin	–	–	64	24	64	64	16	64	64	12	8
	VAN	Vancomycin	–	–	>256	12	>256	>256	64	>256	>256	48	<256
	ERY	Erythromycin	–	–	>256	>256	>256	>256	>256	>256	>256	96	<256
	TRS	Trimethoprim-sulfamethoxazole	–	–	4	1.5	3	>32	>32	>32	4	2	8

The following strains were investigated for antibiotic sensitivity: PA14 WT, a conditional surA mutant grown in the absence (surA) and the presence of 0.2% arabinose (surA SurA+), the bamB deletion mutant (bamB) and a conditional bamB deletion mutant grown in the presence of 0.2% arabinose (bamB BamB+). Reduction of MIC values compared to WT is marked in red. Bold face indicates reduction of MIC values below the breakpoint.