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. Author manuscript; available in PMC: 2019 Feb 28.
Published in final edited form as: Bone Marrow Transplant. 2015 Feb 9;50(5):628–636. doi: 10.1038/bmt.2014.323

Table 1:

Comparative analysis of current retrospective studies of reduced intensity conditioning (RIC) and myeloablative conditioning (MAC) allo-SCT for myelofibrosis (MF) patients

Reference N Years Preparative regimen Median age (range) OS GVHD NRM Relapse
Guardiola et al.14 55 1979–1997 MAC (TBI, 63%) 42 (4–53) 5 years, 47% aGVHD, 60% cGVHD, 60% 27% 18%
Kerbauy et al.15 104 1990–2005 MAC, 95; RIC, 9 49 (18–70) 2 years, 70%; 5 years, 61% aGVHD, 64% cGVHD, 84% 32% 10.5%
Abelsson et al.16 92 1982–2009 MAC, 40; RIC, 52 46 MAC 55 RIC 2 years, 55%/75%; 5 years, 49%/59% aGVHD, 75% MAC 28% RIC 32% 24% 10%
Nivison-Smith et al.17 57 1993–2005 MAC, 40; RIC, 17 47 (16–71) 2 years, 59%/66%; 5 years, 58% aGVHD, 37% 25% 12%
Kroger et al.19 103 2002–2007 RIC, all (BU/Flu) 55 (32–68) 5 years, 67% aGVHD, 27% cGVHD, 49% 19% 29%
Gupta et al.20 233 1997–2010 RIC, all 55 (19–79) 5 years, 47% aGVHD, 37% (day 100) cGVHD-42% 18% 43%