Fig. 1.
Associations between processing speed (PS) and cerebral blood flow (CBF). Slower PS was associated with lower CBF in two clusters: one encompassing bilateral caudate nucleus and thalamus (peak t = 4.24; p value at peak-t = 3.1 × 10− 5; x, y, z = − 2, − 4, 2; kvoxels = 48), as well as a separate cluster in the frontal lobe including bilateral superior frontal gyrus (Fig. 1; peak t = 4.79; p value at peak- t = 3.9 × 10− 6; x, y, z = − 14, 52, 38; kvoxels = 55). Activation clusters are overlaid on a 4 mm resolution brain image generated by averaging across all subject-specific structural images