Table 1.
Characteristics | Normal (n=142) | IGR (n=245) | T2DM (n=388) | F-value | P-value | F-value adjusted for age | P-value adjusted for age |
---|---|---|---|---|---|---|---|
| |||||||
Age, years | 73.5±11.0 | 75.7±11.1 | 76.7±10.8 | 5.00 | 0.00 | ||
Height, cm | 171.13±4.88 | 170.12±5.44 | 170.3±5.90 | 1.71 | 0.18 | ||
Weight, kg | 73.35±10.26 | 72.4±10.27 | 71.08±10.34 | 6.81 | 0.00 | 2.13 | 0.12 |
BMI, kg/m2 | 24.0±2.81 | 24.32±2.82 | 24.45±3.03 | 1.43 | 0.24 | 2.82 | 0.06 |
SBP, mmHg | 129.73±18.62 | 129.15±16.71 | 132.31±16.75 | 6.89 | 0.00 | 2.67 | 0.07 |
DBP, mmHg | 77.10±10.87 | 74.37±9.96 | 72.75±10.72 | 5.23 | 0.00 | 0.39 | 0.68 |
FPG, mmol/L | 5.17±0.38 | 5.44±0.50 | 6.38±1.60 | 9.23 | 0.00 | 8.90 | 0.00 |
PPG, mmol/L | 5.92±0.76 | 8.23±1.28 | 11.13±2.90 | 5.87 | 0.00 | 6.48 | 0.00 |
FCP, ng/mL | 2.34±1.18 | 2.61±1.11 | 2.42±0.82 | 1.05 | 0.35 | ||
FINS, mU/L | 7.62±5.03 | 8.55±4.86 | 8.16±5.44 | 0.40 | 0.67 | ||
HbA1c, % (mmol/mol) | 5.77±0.36 (40±3.9) | 6.30±0.94 (45±10.3) | 6.59±1.01 (49±11.0) | 6.10 | 0.00 | 3.60 | 0.03 |
TC, mmol/L | 4.86±0.90 | 4.71±0.95 | 4.5±0.95 | 9.43 | 0.00 | 6.33 | 0.00 |
TG, mmol/L | 1.43±0.82 | 1.47±0.91 | 1.48±0.92 | 5.06 | 0.00 | 8.58 | 0.00 |
HDL-C, mmol/L | 1.33±0.33 | 1.31±0.34 | 1.27±0.35 | 5.82 | 0.00 | 6.88 | 0.00 |
LDL-C, mmol/L | 3.08±0.81 | 2.98±0.81 | 2.82±0.84 | 6.27 | 0.00 | 8.35 | 0.00 |
Serum Cr, µmol/L | 85.23±14.54 | 86.38±18.78 | 87.19±21.97 | 5.94 | 0.00 | 5.75 | 0.00 |
ALT, U/L | 17.60±10.79 | 19.67±11.21 | 20.28±11.75 | 2.83 | 0.06 | ||
UA, µmol/L | 353.58±69.55 | 356±75.15 | 350.68±79.57 | 1.00 | 0.37 |
Notes: Values are presented as mean ± SD. ANOVA was used for analysis.
Abbreviations: ALT, alanine aminotransferase; BMI, body mass index; Cr, creatinine; FCP, fasting C-peptide; FINS, fasting serum insulin; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; IGR, impaired glucose regulation; LDL-C, low-density lipoprotein cholesterol; PPG, postprandial glucose; T2DM, type 2 diabetes mellitus; TC, total cholesterol; TG, triglyceride; UA, uric acid.