Table 4.

Markers of bone metabolism and bone turnover in the three glycometabolism groups

Marker	Normal	IGR	T2DM	F-value	P-value	F-value adjusted for serum Cr, age, BMI	P-value adjusted for serum Cr, age, BMI
Ca, mmol/L	2.36±0.08	2.35±0.09	2.36±0.09	5.18	0.00	3.52	0.03
P, mmol/L	1.09±0.15	1.08±0.14	1.1±0.15	2.89	0.06	3.94	0.02
ALP, U/L	63.85±17.70	62.83±16.22	63.14±17.59	1.31	0.27	1.51	0.23
25(OH)D, ng/mL	20.36±8.94	21.82±9.30	22.49±10.14	5.33	0.00	4.63	0.01
PTH, pg/mL	38.10±14.36	41.09±15.97	39.17±15.27	8.21	0.00	1.72	0.18
β-CTX, ng/mL	0.30±0.15	0.29±0.16	0.26±0.16	6.40	0.00	3.84	0.02
BGP, ng/mL	18.25±8.32	16.56±7.85	15.05±7.03	5.34	0.00	7.75	0.00
P1NP, ng/mL	38.12±14.28	35.85±17.45	34.09±22.12	10.24	0.00	3.79	0.02

Notes: Values are presented as mean ± SD. ANOVA was used for analysis.

Abbreviations: BGP, bone gamma-carboxyglutamic acid protein (osteocalcin); BMI, body mass index; Ca, calcium; Cr, creatinine; β-CTX, β-carboxy-terminal cross-linking telopeptide of type I collagen; 25(OH)D, 25-hydroxyvitamin D; IGR, impaired glucose regulation; P, phosphorus; P1NP, procollagen type 1 intact N-terminal propeptide; PTH, parathyroid hormone; T2DM, type 2 diabetes mellitus.