Skip to main content
. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: J Pediatr. 2018 Oct 3;204:148–156.e4. doi: 10.1016/j.jpeds.2018.08.059

Table 5.

Model-Adjusted Proportions of Positive Screens on BITSEA by Neuroimaging Findings at 18- to 22-Months

Neuroimaging Findings Problem
Competence
Adjusted % (95% CI) p-value Adjusted % (95% CI) p-value
Early CUS
    Normal 0.31 (0.23, 0.40) REF 0.19 (0.11, 0.30) REF
    No IVH grade 3–4/cPVL 0.33 (0.21, 0.47) 0.753 0.21 (0.11, 0.36) 0.718
    IVH grade 3–4/cPVL 0.28 (0.15, 0.46) 0.754 0.15 (0.06, 0.31) 0.518
Late CUS
    Normal 0.32 (0.24, 0.42) REF 0.17 (0.10, 0.28) REF
    No IVH grade 3–4/cPVL 0.29 (0.19, 0.41) 0.521 0.23 (0.13, 0.38) 0.237
    IVH grade 3–4/cPVL 0.21 (0.08, 0.44) 0.267 0.18 (0.07, 0.41) 0.908
Severity of WMA
    Normal 0.34 (0.23, 0.48) REF 0.15 (0.08, 0.28) REF
    Mild 0.30 (0.22, 0.39) 0.415 0.20 (0.12, 0.31) 0.352
    Moderate 0.31 (0.19, 0.46) 0.649 0.18 (0.09, 0.34) 0.640
    Severe 0.26 (0.09, 0.54) 0.518 0.27 (0.10, 0.56) 0.282
Lesions
    No lesions 0.31 (0.23, 0.40) REF 0.18 (0.11, 0.29) REF
Non-cerebellar lesions only 0.27 (0.18, 0.38) 0.446 0.20 (0.11, 0.34) 0.638
    Cerebellar lesions 0.37 (0.24, 0.53) 0.356 0.20 (0.10, 0.35)
Significance of cerebellar lesions
    No cerebellar lesions 0.29 (0.22, 0.38) REF 0.19 (0.11, 0.29) REF
    Non-significant lesions 0.37 (0.20, 0.59) 0.423 0.17 (0.06, 0.38) 0.783
    Significant lesions 0.38 (0.22, 0.56) 0.317 0.21 (0.10, 0.40) 0.688

Note: REF=reference category; means are adjusted for center, birthweight, gestational age, multiple gestation, race/ethnicity, Medicaid enrollment, gender, antenatal steroids, C-section, late-onset sepsis, surgery for ROP, NEC, or PDA, postnatal steroids, and BPD.