Table 3.
Multivariable regression analysis showing baseline factors associated with an individual TTR below 60% among patients with atrial fibrillation instituted on warfarin treatment
| OR | 95% CI for OR | p | |
|---|---|---|---|
| Age | 0.99 | 0.98–0.99 | < 0.001 |
| Female sex | 0.98 | 0.93–1.04 | 0.481 |
| Stroke | 0.85 | 0.79–0.91 | < 0.001 |
| TIA | 0.91 | 0.82–1.00 | 0.056 |
| Hypertension | 1.25 | 1.18–1.32 | < 0.001 |
| Diabetes mellitus | 1.25 | 1.16–1.33 | < 0.001 |
| Myocardial infarction | 1.07 | 1.00–1.14 | 0.045 |
| Cancer | 1.21 | 1.11–1.31 | < 0.001 |
| Chronic obstructive pulmonary disease | 1.45 | 1.33–1.59 | < 0.001 |
| Renal failure | 1.47 | 1.29–1.68 | < 0.001 |
| Excessive alcohol use | 2.72 | 2.27–3.24 | < 0.001 |
| Dementia | 1.47 | 1.02–2.12 | 0.038 |
| Liver disease | 1.27 | 0.97–1.67 | 0.083 |
| History of fall | 1.23 | 1.11–1.35 | < 0.001 |
| Anemia | 1.36 | 1.22–1.51 | < 0.001 |
| Previous major bleeding | 1.00 | 0.85–1.16 | 0.971 |
| Previous gastrointestinal bleeding | 0.99 | 0.82–1.20 | 0.905 |
| Previous intracranial bleeding | 1.21 | 0.95–1.55 | 0.116 |
OR odds ratio, CI confidence interval