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. 2019 Feb 19;19(2):1–86.

Table 1:

Study, Patient, and Intervention Characteristics: Randomized Controlled Trials on Compression Stockings

Author, Year Country Study Objective Randomized Groupsa Stocking Type Patients Na Female/Male N Mean Age Years (SD)a Outcome Measured
Kapp et al, 201326 Australia To compare the effect of moderate pressure with high pressure on recurrence of VLU and patient adherence 23–32 mm Hg vs.
34–46 mm Hg
Venosan 5000 range, Salzmann, MEDICO, St Gallen, Switzerland
Below knee length
Participants were provided with two stockings for wear on the study leg only
93
Moderate: 49
High: 44
68/25 23–32 mm Hg: 79.04 (10.40)
34–46 mm Hg: 78.27 (10.56)
Recurrence rate
Time to recurrence
Adherence rate
Adverse effects
Clarke-Moloney et al, 201425 Ireland To compare the effect of two European classes of MCS on recurrence of VLU and patient adherence 18–21 mm Hg vs.
23–32 mm Hg
Mediven elegance (closed toe) or Mediven plus (open toe) 100
18–21 mm Hg: 50
23–32 mm Hg: 50
NA 18–21 mm Hg: 69.7
23–32 mm Hg: 68.9
Recurrence rate
Adherence rate
Nelson et al, 200627 United Kingdom To compare the effect of two European classes of MCS on recurrence of VLU and patient adherence 18–24 mm Hg vs.
25–35 mm Hg
Jobst or Medi
Knee or thigh length
300
18–24 mm Hg: 151
25–35 mm Hg: 149
18–24 mm Hg: 92/59
25–35 mm Hg: 83/66
18–24 mm Hg: 65.1 (12.9)
25–35 mm Hg: 63.6 (11.4)
Recurrence rate
Time to recurrence
Adherence rate
Vandongen & Stacey, 200028 Australia To compare the effect of MCS with no MCS on reducing the area of lipodermatosclerosis and recurrence of VLU MCS with pressure of 35–45 mm Hg vs. no MCS Venosan 2003
Below knee length
153
MCS: 72
No MCS: 81
NA 67 (range, 37–85) Recurrence rate
Adherence rate

Abbreviations: MCS, medical compression stocking; NA, not available; SD, standard deviation; VLU, venous leg ulcer.

a

mm Hg stocking pressure.