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. 2019 Feb 19;19(6):1–199.

Table 10:

Effectiveness of Cognitive Behavioural Therapy Interventions, Reference Case Analysis: Anxiety Disorders

Model Parameter Mean (95%CI/SE)a SMD (95%CI)b Source
Probability of response (improvement)
Unguided iCBT 0.67 (0.58–0.73) 0.66 (0.32–1.00) Adelman, 20147
Guided iCBT 0.74 (0.69–0.78) 0.84 (0.45–1.23) Arnberg et al, 201420
Individual face-to-face CBT 0.73 (0.66–0.77) NA Dedert et al, 201723;
Andrews et al, 201821;
Adelman et al, 20147
Group face-to-face CBT 0.73 (0.66–0.77) NA Dedert et al, 201723;
Andrews et al, 201821;
Adelman et al, 20147
Medication 0.70   Koeser et al, 201593
Probability of recovery
Unguided iCBT 0.38 (0.09) NA Kaltenthaler et al, 200650
Guided iCBT 0.48 (0.23–0.60) 0.22 (0.59–1.07) Andrews et al, 201821
Individual face-to-face CBT 0.66 (0.62–0.68) NAc Biesheuvel-Leliefeld, 201696
Group face-to-face CBT 0.63 (0.59–0.66) NAc Churchill et al, 200197
Medication 0.62 (0.58–0.66) NAc Cipriani et al, 201498

Abbreviations: CBT, cognitive behavioural disorder; CI, confidence interval; iCBT, internet-delivered CBT; NA, not applicable; SMD, standardized mean difference.

a

Beta distributions assigned in probabilistic sensitivity analysis to all parameters for which 95% CI or SE were specified in Table 9b. Two parameters of the beta distribution (α, β) are derived from the mean and SE (stated for each model parameter). Formulas for these calculations, derived from the mean and SE (provided in the Tree Age software) are α = ([Mean2] × [1 – Mean])/([SE2] – Mean); β = ([{1 – Mean} × {1 – Mean}] × Mean)/([SE2] – 1).

b

Original value, reported in the article and clinical review.

c

Reported risk of recurrence, in-person CBT vs. usual care in Biesheuvel-Leliefeld, 2016 and group CBT, in Churchill, 2011, and sertraline in Cipriani, 2014, details provided in our prior report.77