Table 10:
Model Parameter | Mean (95%CI/SE)a | SMD (95%CI)b | Source |
---|---|---|---|
Probability of response (improvement) | |||
Unguided iCBT | 0.67 (0.58–0.73) | 0.66 (0.32–1.00) | Adelman, 20147 |
Guided iCBT | 0.74 (0.69–0.78) | 0.84 (0.45–1.23) | Arnberg et al, 201420 |
Individual face-to-face CBT | 0.73 (0.66–0.77) | NA | Dedert et al, 201723; Andrews et al, 201821; Adelman et al, 20147 |
Group face-to-face CBT | 0.73 (0.66–0.77) | NA | Dedert et al, 201723; Andrews et al, 201821; Adelman et al, 20147 |
Medication | 0.70 | Koeser et al, 201593 | |
Probability of recovery | |||
Unguided iCBT | 0.38 (0.09) | NA | Kaltenthaler et al, 200650 |
Guided iCBT | 0.48 (0.23–0.60) | 0.22 (0.59–1.07) | Andrews et al, 201821 |
Individual face-to-face CBT | 0.66 (0.62–0.68) | NAc | Biesheuvel-Leliefeld, 201696 |
Group face-to-face CBT | 0.63 (0.59–0.66) | NAc | Churchill et al, 200197 |
Medication | 0.62 (0.58–0.66) | NAc | Cipriani et al, 201498 |
Abbreviations: CBT, cognitive behavioural disorder; CI, confidence interval; iCBT, internet-delivered CBT; NA, not applicable; SMD, standardized mean difference.
Beta distributions assigned in probabilistic sensitivity analysis to all parameters for which 95% CI or SE were specified in Table 9b. Two parameters of the beta distribution (α, β) are derived from the mean and SE (stated for each model parameter). Formulas for these calculations, derived from the mean and SE (provided in the Tree Age software) are α = ([Mean2] × [1 – Mean])/([SE2] – Mean); β = ([{1 – Mean} × {1 – Mean}] × Mean)/([SE2] – 1).
Original value, reported in the article and clinical review.
Reported risk of recurrence, in-person CBT vs. usual care in Biesheuvel-Leliefeld, 2016 and group CBT, in Churchill, 2011, and sertraline in Cipriani, 2014, details provided in our prior report.77