Table A9:
Health State Utilities Used in the Economic Model
| Model Parameter | Mean (SD/SE, 95% CI)a | Distributionb | Source |
|---|---|---|---|
| Utilities | |||
| Acute phase, untreated new major depression | Beta | Mohiuddin and Payne, 2014153 | |
| Mild MDE | 0.69 (SD 0.14) | ||
| Moderate to severe MDE | 0.52 (SD 0.28) | ||
| Past major depression | Beta | Schaffer et al, 2002102 | |
| Mild MDE | 0.79 (SD 0.28) | ||
| Moderate to severe MDE | 0.67 (SD 0.36) | ||
| Guided iCBT | Beta | Hedman et al, 201158,104 | |
| 4 months | 0.82 (SD 0.18) | ||
| 12 months | 0.85 (SD 0.14) | ||
| Face-to-face CBT | Fixed | King et al, 2000103 | |
| 4 months | 0.85 (NR) | ||
| 12 months | 0.85 (NR) | ||
| Pharmacotherapy only–treated major depression | 0.63 (SD 0.19) | Beta | Revicki and Wood, 1998154 |
| Normal health, well health state | 0.94 (SE 0.03) | Beta | Lenert et al, 2000105 |
| Complex depression state, with treatment, nonhospitalized | 0.52 (SD 0.29) | Beta | Mann et al, 2009,155 Vallejo-Torres et al, 2015156 |
| Complex depression state, severe phase, hospitalized | 0.34 (SE 0.02) | Beta | Mann et al, 2009,155 Vallejo-Torres et al, 2015156 |
Abbreviations: CBT, cognitive behavioural therapy; CI, confidence interval; MDE, major depressive episode; NR, not reported; SD, standard deviation, SE, standard error.
a
Assumed to be the same for anxiety disorders and major depression, based on results of a study in patients with social anxiety disorder.
b
Beta distributions assigned in probabilistic sensitivity analysis (see above formulas for the calculations of the beta distribution's parameters: α and β.