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. 2018 Oct 12;42(1):64–80. doi: 10.1007/s10753-018-0873-9

Fig. 10.

Fig. 10

The effects of catalpol on HCY-induced GRP78 and p65 activations and the effect is associated with inhibiting Nox4. Cells were treated with Nox4 siRNA (50 nM) and 10 μΜ DPI. Western blot analysis was performed using anti-GRP787, anti-p65 antibodies. (a) Effect of catalpol on GRP78 protein expression level treated with Nox4 siRNA. (b) Effect of catalpol on p65 protein expression level treated with Nox4 siRNA. (c) Effect of catalpol on GRP78 protein expression level treated with DPI. (d) Effect of catalpol on p65 protein expression level treated with DPI. Results represent the mean ± S.D. from three independent experiments. ##p < 0.01 vs. control, **p < 0.01 vs. HCY, &&p < 0.01 vs. Nox4 siRNA.