Table 2.

Common patient questions and concerns regarding sacubitril/valsartan

Questions regarding the benefits of sacubitril/valsartan • I have been stable on my current medications. Why would I change? • How will this medication help my heart? What is the purpose of increasing the dose if I am feeling good on this dose and my blood pressure is good? • Why do I have to be on this medication if my blood pressure is not high? Is this medication for blood pressure? • How long will I live if I take all my medications and monitor what I eat and drink? • Will my heart function recover on medications? • Can I come off some medications if my heart function improves? Do I need to take these medications for the rest of my life? • I am trying to avoid an implantable cardioverter–defibrillator. Will this help? Will this medication improve my ejection fraction? Questions regarding possible negative effects of sacubitril/valsartan • I take so many medications. Will they interact with each other and cause harm? • What are the side effects of medications? • If I do not tolerate the medications, what options do I have? Questions regarding the cost of sacubitril/valsartan • Will my insurance pay for the new medications? • How much more does it cost? Other questions/concerns regarding sacubitril/valsartan • Why have my other doctors not mentioned it? • I am afraid to switch to a medication that is not commonly used.