Table 1.
Demographic and clinical data of patients
| Variable | All patients | Eradication failure | Eradication successful | P-value |
|---|---|---|---|---|
| Clinical parameters | ||||
| Number (male/female) | 160 (76/84) | 36 (16/20) | 124 (60/64) | 0.677 |
| Age (years) | 55.42 ± 11.19 | 57.18 ± 12.13 | 53.58 ± 10.75 | 0.328 |
| BMI (kg/m2) | 25.21 ± 3.67 | 26.46 ± 3.64 | 25.76 ± 3.89 | 0.509 |
| Duration of diabetes (years) | 11.76 ± 4.59 | 14.58 ± 5.63 | 9.67 ± 3.71* | 0.001 |
| Drinking alcohol (%) | 44 (27.5) | 16 (44.4) | 28 (22.6)* | 0.010 |
| Smoking (%) | 36 (22.5) | 12 (33.3) | 24 (19.3) | 0.077 |
| Laboratory parameters | ||||
| Hba1c (%) | 7.72 ± 2.41 | 8.14 ± 2.73 | 7.67 ± 2.22 | 0.142 |
| HOMA-IR index | 4.77 (1.25, 4.79) | 4.91 (1.32, 5.24) | 4.64 (0.95, 4.18) | 0.207 |
| TG, mg/dl | 157.48 ± 61.26 | 162.93 ± 67.32 | 150.33 ± 59.08 | 0.345 |
| TC, mg/dl | 182.65 ± 70.18 | 203.85 ± 88.03 | 170.29 ± 67.42 | 0.096 |
| LDL-C, mg/dl | 128.39 ± 39.41 | 147.90 ± 47.81 | 111.25 ± 30.34 | 0.272 |
| HDL-C, mg/dl | 33.59 ± 18.84 | 30.55 ± 17.38 | 36.82 ± 19.04 | 0.520 |
| 25-OHD total, ng/ml | 17.02 ± 7.16 | 15.09 ± 7.72 | 19.87 ± 6.35* | 0.004 |
| <20 ng/ml (%) | 87 (54.3) | 25 (69.5) | 62 (50.0) | 0.057 |
| 20–30 ng/ml (%) | 42 (26.3) | 8 (22.2) | 34 (27.4) | 0.668 |
| >30 ng/ml (%) | 31 (19.4) | 3 (8.3) | 28 (22.6) | 0.060 |
| Medicine | ||||
| Mealtime insulin (%) | 53 (33.1) | 13 (36.1) | 40 (32.3) | 0.690 |
| Sulfonylureas (%) | 51 (31.9) | 12 (33.3) | 39 (28.42) | 0.841 |
| DPP-4 inhibitor (%) | 40 (25) | 9 (25.9) | 31 (25.0) | 1.000 |
| Metformin (%) | 62 (38.8) | 15 (40.7) | 47 (37.9) | 0.701 |
| Alpha-glucosidase inhibitor (%) | 14 (8.8) | 3 (8.3) | 11 (8.9) | 1.000 |
| Aspirin (%) | 88 (55.0) | 21 (58.3) | 67 (54.0) | 0.706 |
| Statins (%) | 106 (66.3) | 22 (61.1) | 84 (67.7) | 0.549 |
| Activated vitamin D (%) | 68 (42.5) | 7 (19.4) | 61 (49.2)* | 0.001 |
| Calcium (%) | 87 (54.4) | 15 (41.7) | 72 (58.64) | 0.090 |
*p < 0.05 vs. eradication failure group
BMI body mass index, HOMA-IR homeostasis model assessment of insulin resistance, TC total cholesterol, HDL‑C high-density lipoprotein cholesterol, LDL‑C low-density lipoprotein cholesterol, TG triglyceride, 25-OHD 25-hydroxyvitamin D, Hba1c glycated hemoglobin