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. 2018 Dec 4;145(3):599–607. doi: 10.1007/s00432-018-2810-6

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — Predictive value for tamoxifen benefit of PTPN2 protein expression. Distant recurrence-free survival (DRFS) for breast cancer patients treated with tamoxifen (Tam) vs no tamoxifen in relation low PTPN2 protein in oestrogen receptor-positive (ER+) tumours (a), high PTPN2 protein expression in ER + tumours (b), low PTPN2 protein expression in ER + tumours with grade 2 or 3 (c), and high PTPN2 protein expression in ER + tumours with grade 2 or 3 (d). P values were estimated with the log rank test