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. 2017 Jan 4;68(2):129–136. doi: 10.1007/s12576-016-0517-5

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© The Author(s) 2017, corrected publication 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Fig. 1 — Effects of intracerebroventricular (icv) administration of ghrelin (1 nmol) or saline pretreatment with an orexin receptor antagonist (DORA, ACT462206; 15 nmol) or saline on cumulative food intake in conscious rats (A). Effects of icv administration of ghrelin (1 nmol) or saline pretreatment with DORA (15 nmol) or saline on cumulative water intake in conscious rats (B). Data for cumulative food intake and water intake are expressed as the mean ± SEM (n = 4–7). *P < 0.05 and **P < 0.01, compared with saline + saline-injected rats. ^# P < 0.05 and ^## P < 0.01, compared with DORA + saline-injected rats. ^† P < 0.05, compared with saline + ghrelin-injected rats