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. 2018 Nov 16;19(2):311–327. doi: 10.1007/s10142-018-0641-9

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Differentially expressed circular RNA (circRNAs) in human CRC tissues (A) and adjacent normal tissues (N). a Hierarchical clustering of differentially expressed circRNAs. b The box plot shows the variations in circRNA expression. c The scatter plot explains the distribution of the data in circRNA profiles. The values of the x- and y-axes in the scatter plot were the averaged normalized signal values of the group (log₂ scales). d The volcano plot illustrates the distribution of the data in circRNA profiles. The green lines in the scatter and volcano plots show the significant fold change (color figure online)