Comparison 1. Percutaneous ethanol injection (PEI) versus percutaneous acetic acid injection (PAI).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Overall survival: all trials	2	185	Hazard Ratio (Random, 95% CI)	1.47 [0.68, 3.19]
1.1 Low risk of bias trial	1	125	Hazard Ratio (Random, 95% CI)	1.13 [0.63, 2.03]
1.2 High risk of bias trial	1	60	Hazard Ratio (Random, 95% CI)	2.64 [0.81, 8.55]
2 Recurrence‐free survival	2	185	Hazard Ratio (Random, 95% CI)	1.42 [0.68, 2.94]
2.1 Low risk of bias trial	1	125	Hazard Ratio (Random, 95% CI)	1.02 [0.66, 1.57]
2.2 High risk of bias trial	1	60	Hazard Ratio (Random, 95% CI)	2.16 [1.11, 4.21]