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. 2015 Jan 26;2015(1):CD006745. doi: 10.1002/14651858.CD006745.pub3

Tsai 2008.

Methods Prospective randomised trial.
Recruitment: July 1998 to July 2004.
Country: Japan.
Participants 125 participants: 55 PEI, 70 PAI.
Child A/Child B‐C: PEI 39/16 PAI 56/14.
Interventions PEI versus PAI.
Outcomes Local tumour recurrence, new tumour recurrence, overall survival, cancer‐free survival.
Inclusion criteria
  • 1 to 3 tumours, each ≤ 4 cm.

  • Tumours were unresectable or surgery refused.

  • INR < 1.5, platelets > 50,000/mm3.

  • No ascites.

  • No previous HCC treatment.

Exclusion criteria
  • Previous HCC treatment.

  • Thrombosis of the portal vein.

  • Distant metastasis.

Follow‐up 2 to 110 months.
Notes Randomisation was unclear. The authors reported a "...somewhat random manner by the operator...". Size of treatment groups differed strongly. People who were unresectable or did not agree to surgery were enrolled. No primary and secondary outcomes were determined, only outcomes in general. Contacting with the author was unsuccessful.

HCC: hepatocellular carcinoma; PEI: percutaneous ethanol injection; INR: International Normalized Ratio; PAI: percutaneous acetic acid injection.