Table 2.
Variable | Odd ratio (95% CI) | p value* |
---|---|---|
Recurrence Score result (per 50-unit increaseb) | 0.06 (0.02, 0.18) | < 0.001 |
Age (years) | 1.00 (0.96, 1.05) | 0.854 |
Baseline tumor size (mm) | 1.00 (0.96, 1.03) | 0.786 |
Grade | ||
1 versus 3 | 0.44 (0.17, 1.09) | 0.074 |
2 versus 3 | 0.81 (0.29, 2.19) | 0.671 |
CI confidence interval
*p value based on the profile likelihood test
aESR1, PGR, and ER gene-group were not included in the prespecified multivariable analysis because they represent individual gene components of the Recurrence Score algorithm
bStatistics were calculated per 50-unit change in Recurrence Score result to facilitate comparison with results of the original validation studies