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. 2018 Oct 29;27(4):1459–1469. doi: 10.1007/s00520-018-4481-x

Table 3.

Number of patients with dose reductions at the second cycle and compliance with guidelines

Standard met and dose reduction in the second cycle
Dose reduction Standard dose
n % n %
Lung cancer
 Yes (with G-CSF) 42 22.5 116 30.1
 Yes (without risk factors) 6 3.2 23 6.0
 Yes (dose reduction without G-CSF) 58 31.0 0 0.0
 Yes (dose reduction, no risk factors, no G-CSF) 13 7.0 0 0.0
 No (overuse: G-CSF without risk factors) 0 0.0 9 2.3
 No (overuse: G-SCF and dose reduction) 11 5.9 0 0.0
 No (underuse: dose reduction and risk factors) 14 7.5 0 0.0
 No (underuse: no G-CSF) 43 23.0 238 61.7
 Gesamt 187 100.0 386 100.0
Breast cancer
 Yes (with G-CSF) 10 34.5 428 55.4
 Yes (without risk factors) 0 0.0 97 12.6
 Yes (dose reduction without G-CSF) 4 13.8 0 0.0
 Yes (dose reduction, no risk factors, no G-CSF) 0 0.0 0 0.0
 No (overuse: G-CSF without risk factors) 0 0.0 36 4.7
 No (overuse: G-SCF and dose reduction) 6 20.7 0 0.0
 No (underuse: dose reduction and risk factors) 6 20.7 0 0.0
 No (underuse: no G-CSF) 3 10.3 211 27.3
Total 29 100.0 772 100.0